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1 contact hour
Recorded Video Courses

A Time and “-plase” for Everything: Updated Management of Acute Ischemic Stroke

Learn about alteplase and tenecteplase, their use, side effects, and pharmacist's role in stroke treatment. Stay updated on guidelines.

David M. Peters Jr
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About this course

Alteplase and tenecteplase are commonly utilized within health-systems requiring rapid decision-making by the healthcare team. These medications include high risk of life-threatening side effects for which patients must be carefully chosen. Pharmacists must be consistently ready to review orders for appropriateness. Recent literature search revealed updates in the timing and dosing scheme related to the use of alteplase for acute ischemic stroke. 2019 Stroke guidelines added a new section on tenecteplase, highly likely to be a new concept among many pharmacists practicing outside of neurology. Endovascular thrombectomy for acute ischemic stroke is a growing topic in neurology and Pharmacists should have a basic understanding of the process and timing of this procedure to understand how to select pharmacotherapy. This activity will be a knowledge-based activity outlining key principles related to the mechanism of action of fibrinolytic therapy (alteplase, tenecteplase) so the audience understands the background of the disease state and our pharmacotherapy goals. A thorough literature review will be provided to understand the efficacy and timing of these agents. A focus on tenecteplase will be provided as this may be very new to many pharmacists since the literature is only about 5 years old. Endovascular procedures will be discussed so pharmacists can visualize the process of selecting patients and the outcomes associated with this therapy. Multiple choice questions will be asked throughout to engage the audience and assess understanding.

Release Date:07/08/2021
Expiration Date:07/08/2024
CE Broker ID20-845769
AGD Number386503
Activity Type:Knowledge-based
Target Audience:Dental Therapist, Speech-Language Pathology Intern, Certified Respiratory Therapist, Speech-Language Pathologist - SA, Occupational Therapy Assistant, Advanced Practice Nurse Prescribers, Pharmacist, Social Worker Intern, Speech-Language Pathology Assistant, Certified Nurse Midwife, Speech-Language Pathologist Special Volunteer, Licensed Social Worker, Licensed Clinical Social Worker, Certified Master Social Worker, Licensed Independent Social Worker, Nursing Assistive Personnel, Expanded Function Dental Assistant, Registered Respiratory Therapist, Dental Hygienist, Certified Nurse Aides, Expanded Function Dental Auxiliary, Advanced Dental Assistant, Registered Nurse Practitioner, Advanced Practice Nurses, Athletic Trainer, Occupational Therapist, Forensic Nurse-CSA, Certified Registered Nurse Anesthetist, Psychiatric Nurse, Clinical Nurse Specialist, APRN - Certified Nurse Midwife, Licensed Practical Nurse, Licensed Independent Clinical Social Worker, Nurse Practitioner, Licensed Psychiatric Technician Nurse, Dentist, Registered Nurse, Licensed Nursing Assistant, Advanced Practice Registered Nurse, Public Health Nurse, Licensed Vocational Nurse, Nursing Home Administrator, Dental Technician, Licensed Masters Social Worker, Community Dental Health Coordinator, Respiratory Therapist, Master's Social Work, Respiratory Care Practitioner Critical Care, Dental Lab, Respiratory Care Practitioner, Speech-Language Pathologist Ltd, Licensed Certified Social Worker, Licensed Baccalaureate Social Worker, Licensed Independent Social Worker Dual, Certified Nursing Assistant, Respiratory Care Practitioner Non-Critical Care, Registered Social Worker Assistant, Denturist, Registered Dental Assistant, General Dentist, Pharmacy Technician, Bachelor's Social Worker, Licensed Independent Social Worker Advanced Practice, Dental Assistant Radiographer, Licensed Graduate Social Worker, Speech-Language Pathologist, Licensed Independent Social Worker Clinical Practice, Dental Assistant
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Course Accreditation

This course is approved for the following professions. You can get more details on each profession by clicking on it.

AchieveCE is an approved provider (Provider #50-20641) of continuing education for occupational therapy professionals.

  • Alabama State Board of Occupational Therapy

  • Arizona Board of Occupational Therapy Examiners

  • Florida Board of Occupational Therapy

  • Georgia State Board of Occupational Therapy

  • Tennessee Board of Occupational Therapy

  • Mississippi State Department of Health – Bureau of Professional Licensure for Occupational Therapists



David Peters is an assistant professor and clinical pharmacist in the Dayton, Ohio area. He completed his PharmD at Ohio Northern University and his residency training at the University of Cincinnati Medical Center. Dr. Peters has held a variety of roles while employed for the Cedarville University School of Pharmacy, including coordination of the Renal Module and Critical Care elective and course participation related to critical care topics. He holds a practice site in the Neuroscience Intensive Care Unit at Miami Valley Hospital where he coordinates pharmaceutical care for patients and provides pharmacology education for both pharmacy and medical learners. His projects include optimization of stroke and epilepsy pharmacology and he has served on multiple process improvement and research projects. In his free time, Dr. Peters enjoys serving in his community and church, hiking, reading, walking his dog and playing board games.​

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What are others saying?

Take a look at what other healthcare professionals are saying about AchieveCE’s continuing education courses.

Dawn O.Nutritionist
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I am always interested in continuing education in the areas of health, wellness, nutrition and mental health. Your course was well written, well organized and helpful in meeting state licensure requirements.

Priya M.Occupational Therapist
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Very well written, easy to digest, time efficient, and straight to the point. Thank you!

Cristina GRegistered Nurse
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I appreciate the convenience of the course being online and accessible through my phone and that it directly reports to CEBroker to support mandated education requirements.

Allison B.Nurse Practitioner
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I really loved this information. I was hospitalized last year for almost a month and I noticed multiple medical errors (not being hooked up to my IV multiple times, given wrong medication which caused my sodium to be very low, etc.) which lengthened my stay. I can now define those exact errors and better understand what happened to me. I hate that these medical errors are so common and I appreciate how well laid out your breakdown and categorization of them was.

Ronald H.Dentist
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I am always looking for concise ,thorough, and up to date continuing education, and this course provided exactly what I was looking for. Thank you

Meghan L.Physician
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Enjoyed this course! It squarely met my license renewal requirement as a physician. It was well-written, and an altogether enjoyable read.


Passing Grade

Participants must score a passing grade of 70% or higher on the activity post-test and complete an activity evaluation. There are no time limits and unlimited test-taking attempts. Credits will be reported automatically to CE Broker if your license information is entered properly in your profile.

Hardware Requirements
  • Windows 8.1
  • Windows 10
  • Mac OS X 10.1+
  • iOS 10+
  • Android 4.3+
Software Requirements
  • Google Chrome
  • Microsft Edge
  • Mozilla Firefox
  • Adobe Acrobat Reader
Network Requirements
  • Broadband Internet Connection: T1
  • Hi-speed DSL or Cable4G cellular connection
$ 7.00