I am always interested in continuing education in the areas of health, wellness, nutrition and mental health. Your course was well written, well organized and helpful in meeting state licensure requirements.
A Time and “-plase” for Everything: Updated Management of Acute Ischemic Stroke
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Course applies toward state CE requirements and hours needed for your FL RN license renewal. View Terms

This course is guaranteed to meet or exceed your expectations for convenience and quality. View Terms
Very well written, easy to digest, time efficient, and straight to the point. Thank you!
I appreciate the convenience of the course being online and accessible through my phone and that it directly reports to support mandated education requirements.
The course was well organized and helpful in meeting state licensure requirements. I found the content to be very informative and practical.
Learn about alteplase and tenecteplase, their use, side effects, and pharmacist's role in stroke treatment. Stay updated on guidelines.

A Time and “-plase” for Everything: Updated Management of Acute Ischemic Stroke
Learn about alteplase and tenecteplase, their use, side effects, and pharmacist's role in stroke treatment. Stay updated on guidelines.
Nationally & state accredited
Course Features
What you'll learn
At the conclusion of this continuing education activity, the participant will be able to:
Explain the mechanism of action of tissue plasminogen activator in a medical emergency.
Review literature regarding the best practice for the use of alteplase and tenecteplase for acute ischemic stroke.
Outline the use of endovascular mechanical thrombectomy for acute ischemic stroke.
Course description
Alteplase and tenecteplase are commonly utilized within health-systems requiring rapid decision-making by the healthcare team. These medications include high risk of life-threatening side effects for which patients must be carefully chosen. Pharmacists must be consistently ready to review orders for appropriateness. Recent literature search revealed updates in the timing and dosing scheme related to the use of alteplase for acute ischemic stroke. 2019 Stroke guidelines added a new section on tenecteplase, highly likely to be a new concept among many pharmacists practicing outside of neurology. Endovascular thrombectomy for acute ischemic stroke is a growing topic in neurology and Pharmacists should have a basic understanding of the process and timing of this procedure to understand how to select pharmacotherapy. This activity will be a knowledge-based activity outlining key principles related to the mechanism of action of fibrinolytic therapy (alteplase, tenecteplase) so the audience understands the background of the disease state and our pharmacotherapy goals. A thorough literature review will be provided to understand the efficacy and timing of these agents. A focus on tenecteplase will be provided as this may be very new to many pharmacists since the literature is only about 5 years old. Endovascular procedures will be discussed so pharmacists can visualize the process of selecting patients and the outcomes associated with this therapy. Multiple choice questions will be asked throughout to engage the audience and assess understanding.
Course content
A Time and “-Plase” for Everything: Updated Management of Acute Ischemic Stroke
About the Faculty
Learning Objectives
Facts About the Brain
With all that power, what happens when blood can’t travel to the brain?
Acute Ischemic Stroke Epidemiology
Pathophysiology
Cerebral Ischemia and Reperfusion
Ischemic Core vs Ischemic Penumbra
Ischemic Stroke Treatment Algorithm
Fibrinolytic therapy
Hemostasis and clot formation
Tissue Plasminogen Activator: Mechanism of Action
Fibrinolytic For Acute Ischemic Stroke
NINDS Trial
ECASS 3 Trial
Time and Efficacy of t-PA
Guideline Direction on t-PA
Thrombolytic Exclusion Criteria
Target: Stroke
Target: Stroke Honor Roll
WARNING: Off-Label Discussion Ahead
Tenecteplase for Acute Ischemic Stroke
Alteplase versus Tenecteplas
EXTEND-IA TNK Study- 2018
What is the best dose of Tenecteplase for Acute Ischemic Stroke?
EXTEND-IA TNK Part 2
Medication Safety Concern
Tenecteplase Key Learning Points
Ischemic Stroke Treatment Algorithm
Interventional Neurology Overview
Mechanical Thrombectomy History
Important Questions to Answer
DAWN Trial
DEFUSE 3 Trial
Key Takeaways
References
Course details
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Instructor

David Peters is an assistant professor and clinical pharmacist in the Dayton, Ohio area. He completed his PharmD at Ohio Northern University and his residency training at the University of Cincinnati Medical Center. Dr. Peters has held a variety of roles while employed for the Cedarville University School of Pharmacy, including coordination of the Renal Module and Critical Care elective and course participation related to critical care topics. He holds a practice site in the Neuroscience Intensive Care Unit at Miami Valley Hospital where he coordinates pharmaceutical care for patients and provides pharmacology education for both pharmacy and medical learners. His projects include optimization of stroke and epilepsy pharmacology and he has served on multiple process improvement and research projects. In his free time, Dr. Peters enjoys serving in his community and church, hiking, reading, walking his dog and playing board games.
Ideal CE course for these professions
This continuing education course is especially relevant for these healthcare professions, but other professionals may also benefit
Accreditations
AchieveCE is an approved provider (Provider #50-20641) of continuing education for occupational therapy professionals.
Frequently asked questions
How many CE credits does this course provide?
This course, "A Time and “-plase” for Everything: Updated Management of Acute Ischemic Stroke ", provides 1 contact hour of continuing education credit upon successful completion.
Is this course accredited?
Yes, this course is accredited by Occupational Therapy, Physical Therapy, Respiratory Therapy, Clinical Laboratory, Athletic Training, Speech-Language Pathology and Audiology, Dentistry, Nursing, Mental Health, Pharmacy. AchieveCE is an approved provider of continuing education for healthcare professionals.
Which professions is this course approved for?
This course is especially relevant for: Dental Therapist, Speech-Language Pathology Intern, Certified Respiratory Therapist, Speech-Language Pathologist - SA, Occupational Therapy Assistant, Advanced Practice Nurse Prescribers, Pharmacist, Social Worker Intern, Speech-Language Pathology Assistant, Certified Nurse Midwife, Speech-Language Pathologist Special Volunteer, Licensed Social Worker, Licensed Clinical Social Worker, Certified Master Social Worker, Licensed Independent Social Worker, Nursing Assistive Personnel, Expanded Function Dental Assistant, Registered Respiratory Therapist, Dental Hygienist, Certified Nurse Aides, Expanded Function Dental Auxiliary, Advanced Dental Assistant, Registered Nurse Practitioner, Advanced Practice Nurses, Athletic Trainer, Occupational Therapist, Forensic Nurse-CSA, Certified Registered Nurse Anesthetist, Psychiatric Nurse, Clinical Nurse Specialist, APRN - Certified Nurse Midwife, Licensed Practical Nurse, Licensed Independent Clinical Social Worker, Licensed Psychiatric Technician Nurse, Nurse Practitioner, Dentist, Registered Nurse, Licensed Nursing Assistant, Advanced Practice Registered Nurse, Public Health Nurse, Licensed Vocational Nurse, Dental Technician, Licensed Masters Social Worker, Community Dental Health Coordinator, Respiratory Therapist, Master's Social Work, Nursing Home Administrator, Respiratory Care Practitioner Critical Care, Dental Lab, Respiratory Care Practitioner, Speech-Language Pathologist Ltd, Licensed Certified Social Worker, Licensed Baccalaureate Social Worker, Licensed Independent Social Worker Dual, Respiratory Care Practitioner Non-Critical Care, Registered Social Worker Assistant, Denturist, Registered Dental Assistant, General Dentist, Pharmacy Technician, Bachelor's Social Worker, Licensed Independent Social Worker Advanced Practice, Dental Assistant Radiographer, Licensed Graduate Social Worker, Speech-Language Pathologist, Licensed Independent Social Worker Clinical Practice, Dental Assistant. Other healthcare professionals may also benefit from this continuing education content.
How do I report my CE credits after completing this course?
Your credits are automatically and instantly reported to CE Broker and CPE Monitor upon successful completion. No manual reporting is required on your part.
Will I receive a certificate of completion?
Yes, you will receive a certificate of completion immediately after finishing the course and passing the assessment. The certificate can be downloaded and printed directly from your account.
What is your refund policy?
We offer a 30-day money-back guarantee. If you are not satisfied with your purchase, you can request a full refund within 30 days of purchase.
How long do I have to complete this course?
You have unlimited time to complete the course at your own pace. Once purchased, the course is available in your account until its expiration date. You can pause and resume at any time.
Most helpful reviews
I am always interested in continuing education in the areas of health, wellness, nutrition and mental health. Your course was well written, well organized and helpful in meeting state licensure requirements.
Very well written, easy to digest, time efficient, and straight to the point. Thank you!
I appreciate the convenience of the course being online and accessible through my phone and that it directly reports to CEBroker to support mandated education requirements.
I really loved this information. I was hospitalized last year for almost a month and I noticed multiple medical errors (not being hooked up to my IV multiple times, given wrong medication which caused my sodium to be very low, etc.) which lengthened my stay. I can now define those exact errors and better understand what happened to me. I hate that these medical errors are so common and I appreciate how well laid out your breakdown and categorization of them was.
Very well written, easy to digest, time efficient, and straight to the point. Thank you!
I appreciate the convenience of the course being online and accessible through my phone and that it directly reports to CEBroker to support mandated education requirements.
I really loved this information. I was hospitalized last year for almost a month and I noticed multiple medical errors (not being hooked up to my IV multiple times, given wrong medication which caused my sodium to be very low, etc.) which lengthened my stay. I can now define those exact errors and better understand what happened to me. I hate that these medical errors are so common and I appreciate how well laid out your breakdown and categorization of them was.
Buy with confidence with money back guarantees

This course is guaranteed to meet or exceed your expectations for convenience and quality. View Terms

Includes all state CE requirements and hours needed for your license renewal. View Terms
Requirements & disclosures
Financial Disclosures
This activity was developed by AchieveCE free of any commercial support. The following individuals have indicated that they have no financial relationships with an ineligible company that may impact upon this activity:
David M. Peters Jr, PharmD, BCCCP - Content Expert and Faculty
Patricia Dunn, DNP, APRN, FNP-BC - Nurse Planner
Pete Kreckel, RPh - Pharmacist Planner
Marie T. Fluent, DDS, CDIPC - Dentist Planner
Gracielle Tubera - Content Reviewer
Luke Porter – Content Reviewer
Dianne Arroyo - Activity Publisher
Passing Grade
Participants must achieve a passing score on the activity post-test, which may be 70% or 80%, depending on the course. They must also complete an activity evaluation. There are no time limits and unlimited test-taking attempts. Credits will be reported automatically to CE Broker if your license information is entered correctly in your profile.
Hardware Requirements
Windows 8.1, Windows 10, Mac OS X 10.1+, iOS 10+, Android 4.3+
Software Requirements
Google Chrome, Microsoft Edge, Mozilla Firefox, Adobe Acrobat Reader
Network Requirements
Broadband Internet Connection: T1, Hi-speed DSL or Cable4G cellular connection
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